Flourish As You Age: THRIVING IN TIMES OF STRUGGLE
What does it mean to flourish when the systems we depend on are under strain?
Flourish in Times of Struggle is a new podcast series for people who want to move beyond personal resilience and grapple with the deeper structures that shape our lives. In this opening episode, Michael C. Patterson introduces the series’ focus on systems, legitimacy, and collective action—and invites listeners to think together about how healthier, more democratic forms of governance might emerge.
Earlier Flourish As You Age podcasts focused more on personal change and development to promote brain health and mental management.
Flourish As You Age: THRIVING IN TIMES OF STRUGGLE
BRAIN - Jesse Wiley, Part 2, What Causes Alzheimer's and What Can We Do To Prevent It?
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Jesse Wiley discusses his work on the TREAT-AD project and their attempt to identify new candidates for drug development to protect against Alzheimer's. Jesse explains that he and his team have identified 15 biological domains that are associated with the development of Alzheimer's (not 18 as I say in the podcast).
Intriguingly, Mitochondrial malfunction and chronic immune response rose to the top of the list of domains.
Jesse also explains "pseudotime" which is a new tool for tracking the trajectory of disease development.
Our discussion of mitochondrial malfunction led us to discussions of epigenetic factors, and the role of behavior and lifestyle interventions.
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